Hemophilia and Von Willebrand Disease: Factor VIII and Von Willebrand Factor 2017 Original PDF

Hemophilia and Von Willebrand Disease: Factor VIII and Von Willebrand Factor is an essential reference on the important role these essential blood-clotting proteins play in research and clinical medicine. Clinicians and researchers are faced with the challenge of staying current on the vast amounts of research that is now generated . The reference to Janus in the title refers to the two roles of the Factor VIII/Von Willebrand Factor Complex: initiation of coagulation and propagation of clot formation. The complex prevents bleeding in hemophilia and Von Willebrand disease but also augments arterial and venous thrombosis.